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undifferentiated connective tissue disease : ウィキペディア英語版
undifferentiated connective tissue disease

Undifferentiated connective tissue disease (UCTD) is a disease in which the body mistakenly attacks its own tissues. It is diagnosed when there is evidence of an existing autoimmune condition which does not meet the criteria for any specific autoimmune disease, such as systemic lupus erythematosus or scleroderma.〔 Latent lupus and incomplete lupus are alternative terms that have been used to describe this condition.〔
The term is sometimes used interchangeably with mixed connective tissue disease, an overlap syndrome. However, MCTD is thought by some researchers to be a clinically distinct entity and is strongly associated with the presence of high titers of ribonucleoprotein (RNP) antibodies.〔
It is estimated that up to 25 percent of people with systemic autoimmune disease could be considered to have UCTD.〔
==Signs and symptoms==

Disease presentation varies widely from patient to patient, as UCTD is by definition nonspecific.〔 Symptoms typically include constitutional complaints that are common to connective tissue diseases such as fatigue, a general sense of feeling unwell, and fever.〔
Other symptoms associated with UCTD include:〔
* dry eyes
* dry mouth
* hair loss
* joint inflammation
* joint pain
* oral ulcers
* positive ANA test
* raynaud's phenomenon
* sun sensitive rash
Lung involvement, such as nonspecific interstitial pneumonia, is a possible disease complication.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「undifferentiated connective tissue disease」の詳細全文を読む



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